General Information of This Antibody-drug Conjugate (ADC)
ADC ID
DRG0PVAIN
ADC Name
Alpha-CLDN-VC0101
Synonyms
CLDN18.2-ADC (Pfizer); CLDN18.2 ADC (Pfizer)
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Organization
Pfizer Inc.
Drug Status
Investigative
Indication
In total 2 Indication(s)
Gastric cancer
Clinical candidate
.
Pancreatic cancer
Clinical candidate
.
Drug-to-Antibody Ratio
4
Structure
Antibody Name
Undisclosed
Antigen Name
Claudin-18.2 (CLDN18.2)
 Antigen Info 
Payload Name
Auristatin 0101
 Payload Info 
Therapeutic Target
Microtubule (MT)
 Target Info 
Linker Name
Mc-Val-Cit-PABC
 Linker Info 
Conjugate Type
Site-specific conjugated of maleimidocaproyl with cysteine free thiol via Michael addition.
Combination Type
Pelidotin