Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0PPLRQ
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| ADC Name |
GENA-111-AF
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| Synonyms |
GENA-111 AF; GENA-111AF; GENA-111-ADC; GENA-111 ADC
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| Organization |
Genome & Co.
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| Drug Status |
Investigative
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| Indication |
In total 1 Indication(s)
Epithelial ovarian cancer [ICD11:2B5D]
Investigative
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| Drug-to-Antibody Ratio |
4.26
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| Antibody Name |
GENA-111
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Antibody Info | ||||
| Antigen Name |
Tumor necrosis factor receptor superfamily member 17 (TNFRSF17)
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Antigen Info | ||||
| Payload Name |
Monomethyl auristatin F
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Undisclosed
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| Conjugate Type |
Debiopharms Multilin technology and a stabilized thiol maleimide conjugation.
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