Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0PGBFS
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| ADC Name |
40410803 5F1-MMAF
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| Synonyms |
5F1-MMAF
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| Organization |
Instituto de Biología Molecular y Celular del Cáncer - CSIC.; CIBERONC.; IBSAL.; Catalan Institute of Oncology.; Institut d'Investigació Biomèdica de Bellvitge - IDIBELL - ONCOBELL.
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| Drug Status |
Investigative
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| Structure |
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| Antibody Name |
5F1
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Antibody Info | ||||
| Antigen Name |
Transforming growth factor alpha (TGFA)
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Antigen Info | ||||
| Payload Name |
Monomethyl auristatin F
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Mc-Val-Cit-PABC
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Linker Info | ||||
| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
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