Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0OVAOS
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| ADC Name |
Denintuzumab mafodotin
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| Synonyms |
SGN-19A; SGN-CD19A; Anti-CD19-mafodotin; Anti-CD19-mcMMAF; Anti-CD19-vcMMAE
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| Organization |
Seagen Inc.
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| Drug Status |
Investigative
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| Indication |
In total 8 Indication(s)
Acute lymphoblastic leukemia [ICD11:2B33]
Investigative
B-cell lymphoma [ICD11:2A86]
Investigative
Burkitt lymphoma [ICD11:2A85]
Investigative
Diffuse large B-cell lymphoma [ICD11:2A81]
Investigative
Follicular lymphoma [ICD11:2A80]
Investigative
Mantle cell lymphoma [ICD11:2A85]
Investigative
Non Hodgkin lymphoma [ICD11:2B33]
Investigative
Precursor B-lymphoblastic neoplasms [ICD11:2A70]
Investigative
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| Drug-to-Antibody Ratio |
4
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| Structure |
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| Antibody Name |
Undisclosed
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| Antigen Name |
B-lymphocyte antigen CD19 (CD19)
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Antigen Info | ||||
| Payload Name |
Monomethyl auristatin F
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Maleimido-caproyl
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Linker Info | ||||
| Conjugate Type |
Inter-chain cysteine.
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| Combination Type |
Mafodotin
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| TTD ID | ||||||
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