Antibody-drug Conjugate Information

General Information of This Antibody-drug Conjugate (ADC)
ADC ID
DRG0OQAEX
ADC Name
LNCB74
Synonyms
LN-CB74; LN CB74; LNCB74
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Organization
LegoChem Biosciences, Inc.
Drug Status
Phase 1
Indication
In total 6 Indication(s)
Biliary tract cancer
Phase 1
Clinical Trial
Breast cancer
Phase 1
Clinical Trial
Endometrial cancer
Phase 1
Clinical Trial
Lung cancer
Phase 1
Clinical Trial
Ovarian cancer
Phase 1
Clinical Trial
Solid tumor
Phase 1
Clinical Trial
Drug-to-Antibody Ratio
4
Antibody Name
An anti-human-B7-H4 IgG1k monoclonal antibody
  Antibody Info 
Antigen Name
V-set domain-containing T-cell activation inhibitor 1 (VTCN1)
  Antigen Info 
Payload Name
Monomethyl auristatin E
  Payload Info 
Therapeutic Target
Microtubule (MT)
  Target Info 
Conjugate Type
Undisclosed