Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0OPDMW
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| ADC Name |
Control to 8D302-DXd
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| Synonyms |
8D302-DXd
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| Organization |
Engineering Research Center of Cell & Therapeutic Antibody, Ministry of Education, School of Pharmacy, Shanghai Jiao Tong University,.
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| Drug Status |
Investigative
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| Drug-to-Antibody Ratio |
7.72
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| Structure |
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| Antibody Name |
undisclosed
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Antigen Name |
Undisclosed
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| Payload Name |
DX-8951 derivative (DXd)
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Payload Info | ||||
| Therapeutic Target |
DNA topoisomerase 1 (TOP1)
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Target Info | ||||
| Linker Name |
Mc-Gly-Gly-Phe-Gly
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Linker Info | ||||
| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
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