Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0ONYNZ
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| ADC Name |
LT4212552T ADC43
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| Synonyms |
ADC43
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| Organization |
Daiichi Sankyo Company Limited
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| Drug Status |
Investigative
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| Drug-to-Antibody Ratio |
5.6
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| Structure |
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| Antibody Name |
Trastuzumab
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Antibody Info | ||||
| Antigen Name |
Receptor tyrosine-protein kinase erbB-2 (ERBB2)
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Antigen Info | ||||
| Payload Name |
LT4212552T ADC49 payload
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Payload Info | ||||
| Therapeutic Target |
DNA topoisomerase I (TOP1)
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Target Info | ||||
| Linker Name |
LT4212552T-ADC-6-LINKER
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Linker Info | ||||
| Conjugate Type |
Cysteine-maleimide conjugation
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