Payload Information
General Information of This Payload
| Payload ID | PAY0YMULZ |
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|---|---|---|---|---|---|---|
| Name | LT4212552T ADC49 payload |
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| Synonyms |
SCHEMBL20104681
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| Target | DNA topoisomerase I (TOP1) | |||||
| Structure |
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| Formula | C27H27FN4O6 |
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| Isosmiles | CC(C(F)=C1)=C2CC[C@H](NC(COCN)=O)C3=C2C1=NC(C4=CC([C@@]5(O)CC)=C6COC5=O)=C3CN4C6=O |
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| PubChem CID | ||||||
| InChI |
InChI=1S/C27H27FN4O6/c1-3-27(36)16-6-20-24-14(8-32(20)25(34)15(16)9-38-26(27)35)23-18(30-21(33)10-37-11-29)5-4-13-12(2)17(28)7-19(31-24)22(13)23/h6-7,18,36H,3-5,8-11,29H2,1-2H3,(H,30,33)/t18-,27-/m0/s1
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| InChIKey |
ZFZZEMQDWOCAPE-MYUZEXMDSA-N
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| Pharmaceutical Properties | Molecule Weight |
522.533 |
Polar area |
145.77 |
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Complexity |
1568.537054 |
xlogp Value |
1.56342 |
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Heavy Count |
38 |
Rot Bonds |
5 |
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Hbond acc |
9 |
Hbond Donor |
3 |
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Each Antibody-drug Conjugate Related to This Payload