General Information of This Antibody-drug Conjugate (ADC)
ADC ID
DRG0NKVYN
ADC Name
DMUC-4064A
Synonyms
D-4064A; DMUC 4064A; DMUC 4064A, RG788 2; DMUC-4064A; DMUC4064A; RG 7882; RG-7882; RG7882
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Organization
Genentech, Inc.; Roche Holding AG
Drug Status
Phase 1 (Terminated)
Indication
In total 2 Indication(s)
Ovarian cancer
Phase 1
Clinical Trial
Pancreatic cancer
Phase 1
Clinical Trial
Drug-to-Antibody Ratio
2
Antibody Name
MMUC3333A
 Antibody Info 
Antigen Name
Mucin-16 (MUC16)
 Antigen Info 
Payload Name
Monomethyl auristatin E
 Payload Info 
Therapeutic Target
Microtubule (MT)
 Target Info 
Linker Name
Mc-Val-Cit-PABC
 Linker Info 
Conjugate Type
Reactive Cysteines
Combination Type
vedotin
Puchem SID
472399127 , 404719793
ChEBI ID
CHEMBL4297937