Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0NJCAC
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| ADC Name |
T1LD5
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| Synonyms |
T1-LD5
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| Drug Status |
Investigative
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| Indication |
In total 1 Indication(s)
Small cell lung cancer [ICD11:2C25]
Investigative
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| Drug-to-Antibody Ratio |
2
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| Structure |
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| Antibody Name |
Anti-IL1RL1 mAb
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Antibody Info | ||||
| Antigen Name |
Interleukin-1 receptor-like 1 (IL1RL1)
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Antigen Info | ||||
| Payload Name |
N-methyl-uncialamycin
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Payload Info | ||||
| Therapeutic Target |
Human Deoxyribonucleic acid (hDNA)
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Target Info | ||||
| Linker Name |
Mal-Val-Cit-glucuronide-PABC
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Linker Info | ||||
| Conjugate Type |
Antibody was engineered to have cysteine residues suitable for selective reduction and site-specific conjugation to the linker-drug.
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| Combination Type |
LD5
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