Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0NGSGM
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| ADC Name |
muDS6-SSNPP-MM1-202
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| Synonyms |
muDS6 SSNPP MM1 202
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| Organization |
Sanofi SA
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| Drug Status |
Investigative
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| Indication |
In total 5 Indication(s)
Breast cancer [ICD11:2C60-2C65]
Investigative
Cervical cancer [ICD11:2C77]
Investigative
Colorectal cancer [ICD11:2B91]
Investigative
Ovarian cancer [ICD11:2C73]
Investigative
Pancreatic cancer [ICD11:2C10]
Investigative
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| Drug-to-Antibody Ratio |
3-4
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| Structure |
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| Antibody Name |
Anti-CA6 mAb muDS6
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Antibody Info | ||||
| Antigen Name |
Mucin-1 (MUC1)
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Antigen Info | ||||
| Payload Name |
Mertansine DM1
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Sulfosuccinimidyl-N-succinimidyl-4-(5-nitro-2-pyridyldithio) pentanoate (SSNPP)
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Linker Info | ||||
| Conjugate Type |
Random conjugation through nucleophilic lysines.
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