Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0MXPZY
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| ADC Name |
WO2024140927A1-ADC-F (DAR2)
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| Synonyms |
WO2024140927A1-ADC-F (DAR2)
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| Organization |
WUXI BIOLOGICS (SHANGHAI) CO., LTD.
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| Drug Status |
Investigative
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| Drug-to-Antibody Ratio |
2
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| Structure |
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| Antibody Name |
mAb-D
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Antibody Info | ||||
| Antigen Name |
Vascular endothelial growth factor A (VEGFA)
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Antigen Info | ||||
| Payload Name |
Active metabolite of irinotecan SN38
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Payload Info | ||||
| Therapeutic Target |
DNA topoisomerase 1 (TOP1)
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Target Info | ||||
| Linker Name |
CL2A
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Linker Info | ||||
| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
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| Combination Type |
CL2A-SN38
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