Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0MVRLO
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| ADC Name |
Anti-FGFR2 mAb-12947 SPDB-DM4
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| Synonyms |
Anti-FGFR2-mAb-12947-SPDB-DM4
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| Organization |
Novartis AG
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| Drug Status |
Investigative
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| Indication |
In total 3 Indication(s)
Breast cancer [ICD11:2C60-2C65]
Investigative
Colorectal cancer [ICD11:2B91]
Investigative
Gastric cancer [ICD11:2B72]
Investigative
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| Drug-to-Antibody Ratio |
3-4
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| Antibody Name |
Anti-FGFR2 mAb 12947
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Antibody Info | ||||
| Antigen Name |
Fibroblast growth factor receptor 2 (FGFR2)
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Antigen Info | ||||
| Payload Name |
Mertansine DM4
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
N-succinimidyl 4-(2-pyridyldithio) butanoate (SPDB)
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Linker Info | ||||
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