Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0MJEFF
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| ADC Name |
HER2-gsADC-6
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| Synonyms |
HER2 gsADC 6
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| Drug Status |
Investigative
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| Indication |
In total 2 Indication(s)
Breast cancer [ICD11:2C60-2C65]
Investigative
Gastric cancer [ICD11:2B72]
Investigative
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| Drug-to-Antibody Ratio |
4
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| Antibody Name |
Azido-tagged trastuzumab (Ab2)
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Antibody Info | ||||
| Antigen Name |
Receptor tyrosine-protein kinase erbB-2 (ERBB2)
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Antigen Info | ||||
| Payload Name |
Monomethyl auristatin E
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Bicyclononyne derivative 6e
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Linker Info | ||||
| Conjugate Type |
Glycan-Based Glycosite-Specific conjugate through nucleophilic lysines.
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