Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0LAOIO
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| ADC Name |
hDM2005
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| Synonyms |
HDM2005
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| Organization |
Huadong Medicine (Originator)
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| Drug Status |
Phase 1/2
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| Drug-to-Antibody Ratio |
4
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| Structure |
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| Antibody Name |
Anti-ROR1 antibody
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Antibody Info | ||||
| Antigen Name |
Inactive tyrosine-protein kinase transmembrane receptor ROR1 (ROR1)
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Antigen Info | ||||
| Payload Name |
MMAE
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Mc-Val-Cit-PABC
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Linker Info | ||||
| Conjugate Type |
Random Cysteines
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| Combination Type |
vedotin
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The indication landscape of This ADC(2027 Update)
The clinical trial pipeline of This ADC(2027 Update)
| Indication | Phase 1 | Phase 1/2 | Phase 2 | Phase 2/3 | Phase 3 | New Drug Application | Approved | |||
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| Unspecific non-hodgkin lymphoma |
1 Trials
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| Unspecific solid tumor |
2 Trials
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