Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0KNFGV
|
|||||
|---|---|---|---|---|---|---|
| ADC Name |
Homo-Ang2-Cys5.5 conjugate DAR 8
|
|||||
| Synonyms |
Homo Ang2 Cys5.5 conjugate DAR 8
Click to Show/Hide
|
|||||
| Drug Status |
Investigative
|
|||||
| Indication |
In total 1 Indication(s)
|
|||||
| Drug-to-Antibody Ratio |
8
|
|||||
| Antibody Name |
Anti-EGFRvIII mAb
|
Antibody Info | ||||
| Antigen Name |
Epidermal growth factor receptor variant III (EGFRvIII)
|
Antigen Info | ||||
| Payload Name |
Angiopep-2 TFA
|
Payload Info | ||||
| Linker Name |
Mal-DBCO-PEG3
|
Linker Info | ||||
| Conjugate Type |
Site-specific conjugation through the glutamine 297 by an engineered transglutaminase (mTgase).
|
|||||
