Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0KNFGV
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| ADC Name |
Homo-Ang2-Cys5.5 conjugate DAR 8
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| Synonyms |
Homo Ang2 Cys5.5 conjugate DAR 8
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| Drug Status |
Investigative
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| Indication |
In total 1 Indication(s)
Glioblastoma [ICD11:2A00]
Investigative
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| Drug-to-Antibody Ratio |
8
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| Antibody Name |
Anti-EGFRvIII mAb
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Antibody Info | ||||
| Antigen Name |
Epidermal growth factor receptor variant III (EGFRvIII)
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Antigen Info | ||||
| Payload Name |
Angiopep-2 TFA
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Payload Info | ||||
| Linker Name |
Mal-DBCO-PEG3
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Linker Info | ||||
| Conjugate Type |
Site-specific conjugation through the glutamine 297 by an engineered transglutaminase (mTgase).
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