Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0JKVMP
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| ADC Name |
T-VDXd
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| Synonyms |
T-VDXd
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| Drug Status |
Investigative
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| Drug-to-Antibody Ratio |
8
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| Antibody Name |
Trastuzumab
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Antibody Info | ||||
| Antigen Name |
Receptor tyrosine-protein kinase erbB-2 (HER2 ECD2); Receptor tyrosine-protein kinase erbB-2 (HER2 ECD4)
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Antigen Info | ||||
| Payload Name |
DXd
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Payload Info | ||||
| Therapeutic Target |
DNA topoisomerase 1 (TOP1)
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Target Info | ||||
| Linker Name |
Mc-Val-Ala
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Linker Info | ||||
| Conjugate Type |
Random conjugation through reduced inter-chain cysteines
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