General Information of This Antibody-drug Conjugate (ID: DRG0JKQOU)
ADC Name
HB0052
Synonyms
HB0052
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Organization
Shanghai Huaota Biopharmaceutical (Huaota) (Originator)
Drug Status
Phase 1/2
Drug-to-Antibody Ratio
8
Antibody Name
Anti-CD73 antibody
 Antibody Info 
Antigen Name
Thymidylate 5'-phosphatase (NT5E)
 Antigen Info 
Payload Name
SN-38
 Payload Info 
Payload Target
DNA topoisomerase 1 (TOP1)
 Target Info 
Linker Name
A cleavable linker
 Linker Info 
Conjugate Type
Undisclosed
2027 Update
The disease landscape of This ADC
2027 Update
The clinical trial pipelines of This ADC
Indication Phase 1 Phase 2 Phase 3 Approved
Unspecific solid tumor
1 Trials
Trial ID
NCT06992687; CTR20242618
Sarcoma
1 Trials
Trial ID
NCT06992687; CTR20242618
Gastroesophageal junction adenocarcinoma
1 Trials
Trial ID
NCT06992687; CTR20242618
Gastric cancer
1 Trials
Trial ID
NCT06992687; CTR20242618
Colorectal cancer
1 Trials
Trial ID
NCT06992687; CTR20242618
Pancreatic cancer
1 Trials
Trial ID
NCT06992687; CTR20242618
Lung cancer
1 Trials
Trial ID
NCT06992687; CTR20242618
Breast cancer
1 Trials
Trial ID
NCT06992687; CTR20242618
Ovarian cancer
1 Trials
Trial ID
NCT06992687; CTR20242618
Prostate cancer
1 Trials
Trial ID
NCT06992687; CTR20242618
Kidney cancer
1 Trials
Trial ID
NCT06992687; CTR20242618
Head and neck cancer
1 Trials
Trial ID
NCT06992687; CTR20242618