Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0JJIYH
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| ADC Name |
2A1-LC-Cys418ins-mc-vc-PAB-MMAE TDC
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| Synonyms |
2A1-LC-Cys418ins-mc-vc-PAB-MMAE TDC
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| Organization |
SYSTIMMUNE, INC.
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| Drug Status |
Investigative
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| Drug-to-Antibody Ratio |
1.77
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| Structure |
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| Antibody Name |
2A1-LC-Cys418ins
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Antibody Info | ||||
| Antigen Name |
Epidermal growth factor receptor variant III (EGFRvIII)
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Antigen Info | ||||
| Payload Name |
Monomethyl auristatin E
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Mc-Val-Cit-PABC
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Linker Info | ||||
| Conjugate Type |
Cysteine-maleimide conjugation
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| Combination Type |
Vedotin
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