General Information of This Antibody-drug Conjugate (ADC)
ADC ID
DRG0IZSNN
ADC Name
AZD4512
Synonyms
AZD4512
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Organization
AstraZeneca (Top20 MNC) (Originator)
Drug Status
Phase 1/2
Antibody Name
Anti-CD22 antibody
 Antibody Info 
Antigen Name
B-cell receptor CD22 (CD22)
 Antigen Info 
Payload Name
TOP1 inhibitor
 Payload Info 
Therapeutic Target
DNA topoisomerase 1 (TOP1)
 Target Info 
Linker Name
A cleavable linker
 Linker Info 
Conjugate Type
Undisclosed
The indication landscape of This ADC(2027 Update)
The clinical trial pipeline of This ADC(2027 Update)
Indication Phase 1 Phase 1/2 Phase 2 Phase 2/3 Phase 3 New Drug Application Approved
Unspecific non-hodgkin lymphoma
1 Trials
Trial ID
TWCT00005324; NCT07123454; jRCT2031250366; EUCT2025-522371-29-00
Acute lymphoblastic leukemia
1 Trials
Trial ID
TWCT00005329; NCT07109219; jRCT2031250707; EudraCT2025-522372-93; EUCT2025-522372-93-00