General Information of This Antibody-drug Conjugate (ADC)
ADC ID
DRG0ILDAJ
ADC Name
PTM-001-ADC
Synonyms
PTM 001 ADC; PTM-001 ADC
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Organization
Ptm Therapeutics, Inc.
Drug Status
Clinical candidate
Indication
In total 1 Indication(s)
Colon cancer [ICD11:2B90]
Clinical candidate
Drug-to-Antibody Ratio
1.6
Structure
Antibody Name
Undisclosed
Antigen Name
Undisclosed
Payload Name
Mertansine DM1
 Payload Info 
Therapeutic Target
Microtubule (MT)
 Target Info 
Linker Name
Succinimidyl-4-(N-maleimidomethyl)cyclohexane-1-carboxylate (SMCC)
 Linker Info 
Conjugate Type
Random conjugation through nucleophilic lysines.
Combination Type
Emtansine

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