Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
ADC ID |
DRG0ILDAJ
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ADC Name |
PTM-001-ADC
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Synonyms |
PTM 001 ADC; PTM-001 ADC
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Organization |
Ptm Therapeutics, Inc.
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Drug Status |
Clinical candidate
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Indication |
In total 1 Indication(s)
Clinical candidate
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Drug-to-Antibody Ratio |
1.6
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Structure |
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Antibody Name |
Undisclosed
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Antigen Name |
Undisclosed
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Payload Name |
Mertansine DM1
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Payload Info | ||||
Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
Linker Name |
Succinimidyl-4-(N-maleimidomethyl)cyclohexane-1-carboxylate (SMCC)
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Linker Info | ||||
Conjugate Type |
Random conjugation through nucleophilic lysines.
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Combination Type |
Emtansine
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