Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0IKPNI
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| ADC Name |
TWI852077B-J22
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| Synonyms |
J22
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| Organization |
NOVARTIS AG
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| Drug Status |
Investigative
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| Drug-to-Antibody Ratio |
4
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| Structure |
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| Antibody Name |
Anti-cKIT Fab'3
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Antibody Info | ||||
| Antigen Name |
Mast/stem cell growth factor receptor Kit (KIT)
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Antigen Info | ||||
| Payload Name |
Monomethyl auristatin E
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
TWI852077B-C1-linker
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Linker Info | ||||
| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
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| Combination Type |
Compound (2)
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