Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0IGZRX
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| ADC Name |
GEN-1286
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| Synonyms |
GEN 1286; GEN1286; PRO-1286; PRO 1286; PRO1286
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| Organization |
ProfoundBio (Suzhou) Co., Ltd.
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| Drug Status |
Phase 1/2
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| Indication |
In total 1 Indication(s)
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| Drug-to-Antibody Ratio |
8
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| Antibody Name |
Undisclosed
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| Antigen Name |
Hepatocyte growth factor receptor (MET); Epidermal growth factor receptor (EGFR)
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Antigen Info | ||||
| Payload Name |
Exatecan
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Payload Info | ||||
| Therapeutic Target |
DNA topoisomerase 1 (TOP1)
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Target Info | ||||
| Linker Name |
Cys-11 ADC linker
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Linker Info | ||||
| Conjugate Type |
Undisclosed
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| Combination Type |
sesutecan
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