Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0HWNMQ
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| ADC Name |
39812376 84-SN38
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| Synonyms |
84-SN38
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| Organization |
Eisai Co., Ltd.; NHO Osaka National Hospital.
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| Drug Status |
Investigative
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| Drug-to-Antibody Ratio |
8
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| Structure |
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| Antibody Name |
#84.7
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Antibody Info | ||||
| Antigen Name |
Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6)
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Antigen Info | ||||
| Payload Name |
Active metabolite of irinotecan SN38
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Payload Info | ||||
| Therapeutic Target |
DNA topoisomerase 1 (TOP1)
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Target Info | ||||
| Linker Name |
Undisclosed
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| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
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