Antigen Information

General Information of This Antigen (ID: TAR0QMDMR)
Antigen Name
Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6)
Gene Name
CEACAM6
Gene ID
4680
Synonym
NCA
Sequence
MGPPSAPPCRLHVPWKEVLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLAHNLPQ
NRIGYSWYKGERVDGNSLIVGYVIGTQQATPGPAYSGRETIYPNASLLIQNVTQNDTGFY
TLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPEVQNTTYLWWV
NGQSLPVSPRLQLSNGNMTLTLLSVKRNDAGSYECEIQNPASANRSDPVTLNVLYGPDVP
TISPSKANYRPGENLNLSCHAASNPPAQYSWFINGTFQQSTQELFIPNITVNNSGSYMCQ
AHNSATGLNRTTVTMITVSGSAPVLSAVATVGITIGVLARVALI

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Family
Immunoglobulin superfamily, CEA family
Function
FUNCTION: Cell surface glycoprotein that plays a role in cell adhesion and tumor progression (PubMed:10910050, PubMed:11590190, PubMed:1378450, PubMed:16204051, PubMed:2022629, PubMed:2803308, PubMed:8776764). Intercellular adhesion occurs in a calcium- and fibronectin-independent manner (PubMed:16204051, PubMed:2022629). Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM5 and CEACAM8 (PubMed:11590190, PubMed:16204051, PubMed:2022629, PubMed:2803308, PubMed:8776764). Heterophilic interaction with CEACAM8 occurs in activated neutrophils (PubMed:8776764). Plays a role in neutrophil adhesion to cytokine-activated endothelial cells (PubMed:1378450). Plays a role in cell migration and cell adhesion to endothelial cells (PubMed:16204051). {ECO:0000269|PubMed:10910050, ECO:0000269|PubMed:11590190, ECO:0000269|PubMed:1378450, ECO:0000269|PubMed:16204051, ECO:0000269|PubMed:2022629, ECO:0000269|PubMed:2803308, ECO:0000269|PubMed:8776764}.

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Uniprot Entry
CEAM6_HUMAN
HGNC ID
HGNC:1818 ,
KEGG ID
hsa:4680
Each Antibody-drug Conjugate and Its Component Related to This Antigen
Full List of The ADC Related to This Antigen
The Numbers of ADCs, Their Three Components, Payload Targets, and Corresponding Diseases for This Antigens
ADC Name Payload Target Linker ADC Info
38467634 84-EBET [1]
EBET-1055
Bromodomain and extra-terminal domain family (BET)
Undisclosed
 ADC Info 
39812376 84-EBET [2]
EBET-1593
Undisclosed
Undisclosed
 ADC Info 
39812376 84-SN38 [2]
Active metabolite of irinotecan SN38
DNA topoisomerase 1 (TOP1)
Undisclosed
 ADC Info 
39812376 84-Dxd [2]
DX-8951 derivative (DXd)
DNA topoisomerase 1 (TOP1)
Undisclosed
 ADC Info 
39812376 84-MMAE [2]
Monomethyl auristatin E
Microtubule (MT)
Undisclosed
 ADC Info 
WO2024043319A1 1 [3]
WO2024043319A1 1 payload
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 2
WO2024043319A1 5 payload
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 3.9 [3]
WO2024043319A1 3.9 payload
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 4 [3]
WO2024043319A1 4 payload
Undisclosed
WO2024043319A1 Linker 4
 ADC Info 
WO2024043319A1 5 [3]
WO2024043319A1 5 payload
Undisclosed
CN119630431A-ADC-81-LINKER
 ADC Info 
WO2024043319A1 6 [3]
WO2024043319A1 6 payload
Undisclosed
CN119630431A-ADC-81-LINKER
 ADC Info 
WO2024043319A1 7 [3]
CN119630431A ADC-51 payload
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 8 [3]
CN119630431A ADC-51 payload
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 9 [3]
CN119630431A ADC-51 payload
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 10 [3]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-21-LINKER
 ADC Info 
WO2024043319A1 11 [3]
CN119630431A ADC-51 payload
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 12 [3]
CN119630431A ADC-51 payload
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 13 [3]
WO2024043319A1 13 payload
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 14 [3]
WO2024043319A1 14 payload
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 15 [3]
WO2024043319A1 15 payload
Undisclosed
CN119630431A-ADC-26-LINKER
 ADC Info 
WO2024043319A1 16 [3]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-27-LINKER
 ADC Info 
WO2024043319A1 17 [3]
CN119630431A ADC-51 payload
Undisclosed
WO2024043319A1 Linker 17
 ADC Info 
WO2024043319A1 18 [3]
WO2024043319A1 18 payload
Undisclosed
CN119630431A-ADC-29-LINKER
 ADC Info 
WO2024043319A1 19 [3]
CN119630431A ADC-51 payload
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 20 [3]
WO2024043319A1 20 payload
Undisclosed
WO2024043319A1 Linker 20
 ADC Info 
WO2024043319A1 21 [3]
WO2024043319A1 21 payload
Undisclosed
CN119630431A-ADC-32-LINKER
 ADC Info 
WO2024043319A1 22 [3]
WO2024043319A1 22 payload
Undisclosed
CN119630431A-ADC-33-LINKER
 ADC Info 
WO2024043319A1 23 [3]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-34-LINKER
 ADC Info 
WO2024043319A1 24 [3]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-35-LINKER
 ADC Info 
WO2024043319A1 25 [3]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-36-LINKER
 ADC Info 
WO2024043319A1 26 [3]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-37-LINKER
 ADC Info 
WO2024043319A1 27 [3]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-38-LINKER
 ADC Info 
WO2024043319A1 28 [3]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-39-LINKER
 ADC Info 
WO2024043319A1 29 [3]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-40-LINKER
 ADC Info 
WO2024043319A1 30 [3]
CN119630431A ADC-51 payload
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 31 [3]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-42-LINKER
 ADC Info 
WO2024043319A1 32 [3]
CN119630431A ADC-51 payload
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 33 [3]
WO2024043319A1 33 payload
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 34 [3]
CN119630431A ADC-51 payload
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 35 [3]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-46-LINKER
 ADC Info 
WO2024043319A1 36 [3]
CN119630431A ADC-51 payload
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 37 [3]
CN119630431A ADC-51 payload
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 38 [3]
CN119630431A ADC-51 payload
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 39 [3]
CN119630431A ADC-51 payload
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 40 [3]
CN119630431A ADC-51 payload
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 41 [3]
WO2024043319A1 41 payload
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 42 [3]
CN119630431A ADC-54 payload
Undisclosed
CN119630431A-ADC-53-LINKER
 ADC Info 
WO2024043319A1 43 [3]
WO2024043319A1 43 payload
Undisclosed
CN119630431A-ADC-54-LINKER
 ADC Info 
WO2024043319A1 44 [3]
WO2024043319A1 44 payload
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 45 [3]
WO2024043319A1 45 payload
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 46 [3]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 47 [3]
WO2024043319A1 47 payload
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 48 [3]
WO2024043319A1 48 payload
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 49 [3]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 50 [3]
WO2024043319A1 50 payload
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 51 [3]
WO2024043319A1 51 payload
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 52 [3]
WO2024043319A1 52 payload
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 53 [3]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 54 [3]
WO2024043319A1 54 payload
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 55 [3]
WO2024043319A1 55 payload
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 56 [3]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 57 [3]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 58 [3]
WO2024043319A1 58 payload
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 59 [3]
WO2024043319A1 59 payload
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 60 [3]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 61 [3]
WO2024043319A1 61 payload
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 62 [3]
WO2024043319A1 62 payload
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 63 [3]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 64 [3]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 65 [3]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 66 [3]
WO2024043319A1 66 payload
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 67 [3]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 68 [3]
WO2024043319A1 68 payload
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 69 [3]
WO2024043319A1 69 payload
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 70 [3]
WO2024043319A1 70 payload
Undisclosed
Undisclosed
 ADC Info 
WO2024043319A1 71 [3]
WO2024043319A1 71 payload
Undisclosed
Undisclosed
 ADC Info 
CN119630431A ADC-1 [4]
CN119630431A-ADC-1-PAYLOAD
Undisclosed
Undisclosed
 ADC Info 
CN119630431A ADC-2 [4]
CN119630431A ADC-51 payload
Undisclosed
Undisclosed
 ADC Info 
CN119630431A ADC-3 [4]
CN119630431A-ADC-1-PAYLOAD
Undisclosed
CN119630431A-ADC-3-LINKER
 ADC Info 
CN119630431A ADC-4 [4]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-3-LINKER
 ADC Info 
CN119630431A ADC-5 [4]
CN119630431A-ADC-1-PAYLOAD
Undisclosed
CN119630431A-ADC-5-LINKER
 ADC Info 
CN119630431A ADC-12 [4]
CN119630431A-ADC-1-PAYLOAD
Undisclosed
CN119630431A-ADC-12-LINKER
 ADC Info 
CN119630431A ADC-13 [4]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-12-LINKER
 ADC Info 
CN119630431A ADC-14 [4]
CN119630431A-ADC-14-PAYLOAD
Undisclosed
CN119630431A-ADC-12-LINKER
 ADC Info 
CN119630431A ADC-15 [4]
CN119630431A-ADC-15-PAYLOAD
Undisclosed
CN119630431A-ADC-12-LINKER
 ADC Info 
CN119630431A ADC-16 [4]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-12-LINKER
 ADC Info 
CN119630431A ADC-17 [4]
CN119630431A-ADC-17-PAYLOAD
Undisclosed
CN119630431A-ADC-17-LINKER
 ADC Info 
CN119630431A ADC-18 [4]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-18-LINKER
 ADC Info 
CN119630431A ADC-19 [4]
CN119630431A-ADC-17-PAYLOAD
Undisclosed
CN119630431A-ADC-19-LINKER
 ADC Info 
CN119630431A ADC-20 [4]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-20-LINKER
 ADC Info 
CN119630431A ADC-21 [4]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-21-LINKER
 ADC Info 
CN119630431A ADC-22 [4]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-22-LINKER
 ADC Info 
CN119630431A ADC-23 [4]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-23-LINKER
 ADC Info 
CN119630431A ADC-24 [4]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-24-LINKER
 ADC Info 
CN119630431A ADC-25 [4]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-24-LINKER
 ADC Info 
CN119630431A ADC-26 [4]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-26-LINKER
 ADC Info 
CN119630431A ADC-27 [4]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-27-LINKER
 ADC Info 
CN119630431A ADC-28 [4]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-28-LINKER
 ADC Info 
CN119630431A ADC-29 [4]
CN119630431A-ADC-29-PAYLOAD
Undisclosed
CN119630431A-ADC-29-LINKER
 ADC Info 
CN119630431A ADC-30 [4]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-30-LINKER
 ADC Info 
CN119630431A ADC-31 [4]
CN119630431A ADC-51 payload
Undisclosed
WO2024043319A1 Linker 20
 ADC Info 
CN119630431A ADC-32 [4]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-32-LINKER
 ADC Info 
CN119630431A ADC-33 [4]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-33-LINKER
 ADC Info 
CN119630431A ADC-34 [4]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-34-LINKER
 ADC Info 
CN119630431A ADC-35 [4]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-35-LINKER
 ADC Info 
CN119630431A ADC-36 [4]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-36-LINKER
 ADC Info 
CN119630431A ADC-37 [4]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-37-LINKER
 ADC Info 
CN119630431A ADC-38 [4]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-38-LINKER
 ADC Info 
CN119630431A ADC-39 [4]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-39-LINKER
 ADC Info 
CN119630431A ADC-40 [4]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-40-LINKER
 ADC Info 
CN119630431A ADC-41 [4]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-41-LINKER
 ADC Info 
CN119630431A ADC-42 [4]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-42-LINKER
 ADC Info 
CN119630431A ADC-43 [4]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-43-LINKER
 ADC Info 
CN119630431A ADC-44 [4]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-44-LINKER
 ADC Info 
CN119630431A ADC-45 [4]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-41-LINKER
 ADC Info 
CN119630431A ADC-46 [4]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-46-LINKER
 ADC Info 
CN119630431A ADC-47 [4]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-47-LINKER
 ADC Info 
CN119630431A ADC-48 [4]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-48-LINKER
 ADC Info 
CN119630431A ADC-49 [4]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-49-LINKER
 ADC Info 
CN119630431A ADC-50 [4]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-50-LINKER
 ADC Info 
CN119630431A ADC-51 [4]
CN119630431A ADC-51 payload
Undisclosed
CN119630431A-ADC-51-LINKER
 ADC Info 
CN119630431A ADC-52 [4]
CN119630431A-ADC-52-PAYLOAD
Undisclosed
CN119630431A-ADC-52-LINKER
 ADC Info 
CN119630431A ADC-53 [4]
CN119630431A ADC-54 payload
Undisclosed
CN119630431A-ADC-53-LINKER
 ADC Info 
CN119630431A ADC-54 [4]
CN119630431A ADC-54 payload
Undisclosed
CN119630431A-ADC-54-LINKER
 ADC Info 
CN119630431A ADC-55 [4]
CN119630431A-ADC-55-PAYLOAD
Undisclosed
CN119630431A-ADC-55-LINKER
 ADC Info 
CN119630431A ADC-56 [4]
CN119630431A-ADC-56-PAYLOAD
Undisclosed
CN119630431A-ADC-56-LINKER
 ADC Info 
CN119630431A ADC-57 [4]
CN119630431A-ADC-58-PAYLOAD
Undisclosed
CN119630431A-ADC-56-LINKER
 ADC Info 
CN119630431A ADC-58 [4]
undisclosed
Undisclosed
CN119630431A-ADC-58-LINKER
 ADC Info 
CN119630431A ADC-59 [4]
CN119630431A-ADC-58-PAYLOAD
Undisclosed
CN119630431A-ADC-58-LINKER
 ADC Info 
CN119630431A ADC-60 [4]
CN119630431A-ADC-60-PAYLOAD
Undisclosed
CN119630431A-ADC-32-LINKER
 ADC Info 
CN119630431A ADC-61 [4]
CN119630431A-ADC-60-PAYLOAD
Undisclosed
CN119630431A-ADC-61-LINKER
 ADC Info 
CN119630431A ADC-62 [4]
CN119630431A-ADC-62-PAYLOAD
Undisclosed
CN119630431A-ADC-58-LINKER
 ADC Info 
CN119630431A ADC-63 [4]
CN119630431A-ADC-63-PAYLOAD
Undisclosed
CN119630431A-ADC-58-LINKER
 ADC Info 
CN119630431A ADC-64 [4]
CN119630431A-ADC-64-PAYLOAD
Undisclosed
CN119630431A-ADC-64-LINKER
 ADC Info 
CN119630431A ADC-65 [4]
CN119630431A-ADC-65-PAYLOAD
Undisclosed
CN119630431A-ADC-65-LINKER
 ADC Info 
CN119630431A ADC-66 [4]
CN119630431A-ADC-65-PAYLOAD
Undisclosed
CN119630431A-ADC-66-LINKER
 ADC Info 
CN119630431A ADC-67 [4]
CN119630431A-ADC-67-PAYLOAD
Undisclosed
CN119630431A-ADC-67-LINKER
 ADC Info 
CN119630431A ADC-68 [4]
CN119630431A-ADC-67-PAYLOAD
Undisclosed
CN119630431A-ADC-33-LINKER
 ADC Info 
CN119630431A ADC-69 [4]
CN119630431A-ADC-69-PAYLOAD
Undisclosed
CN119630431A-ADC-66-LINKER
 ADC Info 
CN119630431A ADC-70 [4]
CN119630431A-ADC-70-PAYLOAD
Undisclosed
CN119630431A-ADC-70-LINKER
 ADC Info 
CN119630431A ADC-71 [4]
CN119630431A-ADC-71-PAYLOAD
Undisclosed
CN119630431A-ADC-33-LINKER
 ADC Info 
CN119630431A ADC-72 [4]
CN119630431A-ADC-72-PAYLOAD
Undisclosed
CN119630431A-ADC-70-LINKER
 ADC Info 
CN119630431A ADC-73 [4]
CN119630431A-ADC-73-PAYLOAD
Undisclosed
CN119630431A-ADC-33-LINKER
 ADC Info 
CN119630431A ADC-74 [4]
CN119630431A-ADC-74-PAYLOAD
Undisclosed
CN119630431A-ADC-74-LINKER
 ADC Info 
CN119630431A ADC-75 [4]
CN119630431A-ADC-75-PAYLOAD
Undisclosed
CN119630431A-ADC-75-LINKER
 ADC Info 
CN119630431A ADC-76 [4]
CN119630431A-ADC-76-PAYLOAD
Undisclosed
CN119630431A-ADC-76-LINKER
 ADC Info 
CN119630431A ADC-77 [4]
CN119630431A-ADC-77-PAYLOAD
Undisclosed
CN119630431A-ADC-77-LINKER
 ADC Info 
CN119630431A ADC-78 [4]
CN119630431A-ADC-78-PAYLOAD
Undisclosed
CN119630431A-ADC-78-LINKER
 ADC Info 
CN119630431A ADC-79 [4]
CN119630431A-ADC-79-PAYLOAD
Undisclosed
CN119630431A-ADC-79-LINKER
 ADC Info 
CN119630431A ADC-80 [4]
CN119630431A-ADC-80-PAYLOAD
Undisclosed
CN119630431A-ADC-80-LINKER
 ADC Info 
CN119630431A ADC-81 [4]
CN119630431A-ADC-80-PAYLOAD
Undisclosed
CN119630431A-ADC-81-LINKER
 ADC Info 
CEACAM6 HCAb
 Antibody Info 
ADC Name Payload Target Linker ADC Info
HCAb-ADC [5]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
Undisclosed
 Antibody Info 
ADC Name Payload Target Linker ADC Info
CD66c-DXd [6]
DX-8951 derivative (DXd)
DNA topoisomerase 1 (TOP1)
Mc-Gly-Gly-Phe-Gly
 ADC Info 
References
Ref 1 Delivery of a BET protein degrader via a CEACAM6-targeted antibody-drug conjugate inhibits tumour growth in pancreatic cancer models
Ref 2 Broad-Spectrum Efficacy of CEACAM6-Targeted Antibody-Drug Conjugate with BET Protein Degrader in Colorectal, Lung, and Breast Cancer Mouse Models
Ref 3 Antibody-drug complexes
Ref 4 Antibody-drug conjugates
Ref 5 A novel anti-CEACAM6 heavy-chain antibody-drug conjugate for gastrointestinal cancer therapy
Ref 6 Identification of CD66c as a potential target in gastroesophageal junction cancer for antibody-drug conjugate development