Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0HONIM
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| ADC Name |
IMAB027-Val-Cit-MMAE
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| Synonyms |
Anti-claudin 6 antibody-drug conjugate (Ganymed Pharmaceuticals); anti-claudin 6 antibody-drug conjugate
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| Organization |
Ganymed Pharmaceuticals AG; Astellas Pharma, Inc.
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| Drug Status |
Clinical candidate
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| Indication |
In total 1 Indication(s)
Ovarian cancer [ICD11:2C73]
Clinical candidate
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| Structure |
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| Antibody Name |
IMAB027
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Antibody Info | ||||
| Antigen Name |
Claudin-6 (CLDN6)
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Antigen Info | ||||
| Payload Name |
Monomethyl auristatin E
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Mc-Val-Cit-PABC
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Linker Info | ||||
| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
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| Combination Type |
Vedotin
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