Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0GSGAI
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| ADC Name |
TH2-mpeoDM1
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| Synonyms |
HmD2
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| Drug Status |
Investigative
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| Indication |
In total 2 Indication(s)
Breast cancer [ICD11:2C60-2C65]
Investigative
Lung cancer [ICD11:2C25]
Investigative
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| Drug-to-Antibody Ratio |
2.32
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| Antibody Name |
Anti-DLL4 mAb TH2 (A121C)
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Antibody Info | ||||
| Antigen Name |
Delta-like protein 4 (DLL4)
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Antigen Info | ||||
| Payload Name |
Mertansine DM1
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
BIMPRO
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Linker Info | ||||
| Conjugate Type |
Site-specific conjugation through reduced inter-chain cysteines (Cys 121)
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