Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0GOKCO
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| ADC Name |
HA19-SN38 antibody-drug conjugate
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| Synonyms |
AntiCD19 antibodySN38 antibodydrug conjugate Immunomedics; hA19SN38 ADC Immunomedics; hA19-SN38 antibody-drug conjugate (Immunomedics)
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| Organization |
Immunomedics, Inc.; Gilead Sciences, Inc.
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| Drug Status |
Investigative
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| Indication |
In total 1 Indication(s)
Hematologic cancer [ICD11:2B3Z]
Investigative
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| Structure |
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| Antibody Name |
Anti-CD19 mAb hA19
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Antibody Info | ||||
| Antigen Name |
B-lymphocyte antigen CD19 (CD19)
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Antigen Info | ||||
| Payload Name |
Active metabolite of irinotecan SN38
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Payload Info | ||||
| Therapeutic Target |
DNA topoisomerase 1 (TOP1)
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Target Info | ||||
| Linker Name |
CL2A
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Linker Info | ||||
| Conjugate Type |
Inter-chain cysteine.
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| Combination Type |
Govitecan
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