Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0GERTS
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| ADC Name |
wO2025019776A2ADC-M3
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| Synonyms |
WO2025019776A2ADC-M3
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| Organization |
EXELIXIS, INC.
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| Drug Status |
Investigative
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| Drug-to-Antibody Ratio |
8
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| Structure |
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| Antibody Name |
M3
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Antibody Info | ||||
| Antigen Name |
Inactive tyrosine-protein kinase transmembrane receptor ROR1 (ROR1); Tyrosine-protein kinase transmembrane receptor ROR2 (ROR2)
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Antigen Info | ||||
| Payload Name |
Belotecan
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Payload Info | ||||
| Therapeutic Target |
DNA topoisomerase 1 (TOP1)
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Target Info | ||||
| Linker Name |
Undisclosed
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| Conjugate Type |
site formylglycine residue random conjugation
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| Combination Type |
IIa
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