Antibody Information
General Information of This Antibody
| Antibody ID | ANTI0HHBBZ |
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| Antibody Name | M3 |
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| Organization | EXELIXIS, INC. |
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| Synonyms |
M3
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| Antibody Type | Bispecific antibody (BsAb) |
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| Antibody Subtype | Humanized lgG |
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| Antigen Name | Inactive tyrosine-protein kinase transmembrane receptor ROR1 (ROR1); Tyrosine-protein kinase transmembrane receptor ROR2 (ROR2) |
Antigen Info | ||||
| Click to Show/Hide the Sequence Information of This Antibody | ||||||
| Heavy Chain Sequence |
EVQLVESGGGLVQPGGSLRLSCAASGFTFSSYFIHWVRQAPGKGLEWVAGIYPSEGYTSY
ADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCARYYVSGMDYWGQGTLVTVSSAST KGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLOSSGLY SLSSVVTVPSSSLGTOTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELLGGPSV FLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTY RVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTK NQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQG NVFSCSVMHEALHNHYTQKSLSLSPGK Click to Show/Hide
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| Light Chain Sequence |
EVGSYADPFSVCHFADFVPYCYYGGGPLGLAGSGGSDIQMTQSPSSLSASVGDRVTITCR
ASQSVSSAVAWYQQKPGKAPKLLIYSASSLQSGVPSRFSGSRSGTDFTLTISSLQPEDFA TYYCQQYYYYPGTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREA KVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSP VTKSFNRGEC Click to Show/Hide
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| Light Chain Varible Domain |
EVGSYADPFSVCHFADFVPYCYYGGGPLGLAGSGGSDIQMTQSPSSLSASVGDRVTITCR
ASQSVSSAVAWYQQKPGKAPKLLIYSASSLQSGVPSRFSGSRSGTDFTLTISSLQPEDFA TYYCQQYYYYPGTFGQGTKVEIK Click to Show/Hide
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Each Antibody-drug Conjugate Related to This Antibody