Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0FSKMX
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| ADC Name |
HuRH105-SMCC-DM1
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| Synonyms |
HuRH-105-SMCC-DM1
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| Organization |
ImmunoGen, Inc.
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| Drug Status |
Clinical candidate
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| Indication |
In total 1 Indication(s)
Solid tumors [ICD11:2A00-2A0Z|2B50-2F9Z]
Clinical candidate
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| Structure |
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| Antibody Name |
Undisclosed
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| Antigen Name |
Endoglin (ENG)
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Antigen Info | ||||
| Payload Name |
Mertansine DM1
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Succinimidyl-4-(N-maleimidomethyl)cyclohexane-1-carboxylate (SMCC)
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Linker Info | ||||
| Conjugate Type |
Random conjugation through nucleophilic lysines.
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| Combination Type |
Emtansine
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