Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
ADC ID |
DRG0FKOLH
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ADC Name |
DB-1310
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Synonyms |
DB1310; DB 1310
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Organization |
Duality Biologics
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Drug Status |
Clinical candidate
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Indication |
In total 1 Indication(s)
Solid tumors [ICD11:2A00-2A0Z|2B50-2F9Z]
Clinical candidate
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Drug-to-Antibody Ratio |
8
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Antibody Name |
Undisclosed
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Antigen Name |
Receptor tyrosine-protein kinase erbB-3 (ERBB3)
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Antigen Info | ||||
Payload Name |
Proprietary DNA topoisomerase I inhibitor
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Payload Info | ||||
Therapeutic Target |
DNA topoisomerase 1 (TOP1)
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Target Info | ||||
Linker Name |
Maleimide tetrapeptide-based cleavable linker
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Linker Info | ||||
Conjugate Type |
Duality Immune Toxin Antibody Conjugates (DITAC) platform.
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