Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0FKOLH
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| ADC Name |
DB-1310
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| Synonyms |
DB 1310; DB-1310; DB1310
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| Organization |
Duality Biologics
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| Drug Status |
Phase 1/2
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| Indication |
In total 1 Indication(s)
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| Drug-to-Antibody Ratio |
8
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| Antibody Name |
A humanized anti-HER3 IgG1 monoclonal antibody
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Antibody Info | ||||
| Antigen Name |
Receptor tyrosine-protein kinase erbB-3 (HER3)
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Antigen Info | ||||
| Payload Name |
P1021
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Payload Info | ||||
| Therapeutic Target |
DNA topoisomerase 1 (TOP1)
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Target Info | ||||
| Linker Name |
Maleimide tetrapeptide-based cleavable linker
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Linker Info | ||||
| Conjugate Type |
Random Cysteines
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