Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0FDSXR
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| ADC Name |
J591 DAC
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| Synonyms |
J591 DAC
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| Organization |
Department of Pharmaceutical Engineering, School of Pharmaceutical Sciences, Wuhan University.
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| Drug Status |
Investigative
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| Drug-to-Antibody Ratio |
2
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| Structure |
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| Antibody Name |
J591 THIOMAB
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Antibody Info | ||||
| Antigen Name |
Glutamate carboxypeptidase 2 (FOLH1)
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Antigen Info | ||||
| Payload Name |
GNE-987 (R)
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Payload Info | ||||
| Therapeutic Target |
Bromodomain-containing protein 4 (BRD4)
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Target Info | ||||
| Linker Name |
Mc-Gly-Gly-Phe-Gly
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Linker Info | ||||
| Conjugate Type |
Site-specific bioconjugation via THIOMAB.
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