General Information of This Antibody-drug Conjugate (ADC)
ADC ID
DRG0EZVZS
ADC Name
BYON-4413
Synonyms
BYON 4413; BYON-4413; BYON4413
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Organization
Byondis BV
Drug Status
Phase 1
Indication
In total 2 Indication(s)
Acute myeloid leukaemia
Phase 1
Clinical Trial
Myelodysplastic syndrome
Phase 1
Clinical Trial
Drug-to-Antibody Ratio
Undisclosed
Structure
Antibody Name
A humanized anti-CD123 IgG1 antibody
 Antibody Info 
Antigen Name
Interleukin-3 receptor subunit alpha (IL3RA)
 Antigen Info 
Payload Name
seco-DUBA
 Payload Info 
Therapeutic Target
Human Deoxyribonucleic acid (hDNA)
 Target Info 
Linker Name
Mal-PEG2-Val-Cit-PABA-Cyclization Spacer
 Linker Info 
Conjugate Type
Random Cysteines
Combination Type
duocarmazine