General Information of This Antibody-drug Conjugate (ADC)
ADC ID
DRG0EWPDV
ADC Name
WO2015177360A1 ADC-H8-HC40-vcMMAE
Synonyms
WO2015177360A1_ADC H8 HC40 vcMMAE
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Organization
Byodes Private Ltd.
Drug Status
Investigative
Indication
In total 2 Indication(s)
Breast cancer [ICD11:2C60-2C65]
Investigative
Ovarian cancer [ICD11:2C73]
Investigative
Drug-to-Antibody Ratio
1.7
Antibody Name
Anti-5T4 mAb H8 S40C
 Antibody Info 
Antigen Name
Trophoblast glycoprotein (TPBG)
 Antigen Info 
Payload Name
Monomethyl auristatin E
 Payload Info 
Therapeutic Target
Microtubule (MT)
 Target Info 
Linker Name
Mc-Val-Cit-PABC
 Linker Info 
Conjugate Type
Random conjugation through reduced inter-chain cysteines.
Combination Type
Duocarmazine

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