Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0DJFNE
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| ADC Name |
IMAB362-Val-Cit-MMAE
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| Synonyms |
IMAB362 vcMMAE; IMAB362-vc-MMAE; IMAB362 vc MMAE
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| Organization |
Ganymed Pharmaceuticals AG; Astellas Pharma, Inc.
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| Drug Status |
Clinical candidate
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| Indication |
In total 2 Indication(s)
Gastric cancer [ICD11:2B72]
Clinical candidate
Pancreatic cancer [ICD11:2C10]
Clinical candidate
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| Antibody Name |
IMAB362
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Antibody Info | ||||
| Antigen Name |
Claudin-18.2 (CLDN18.2)
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Antigen Info | ||||
| Payload Name |
Monomethyl auristatin E
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Mc-Val-Cit-PABC
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Linker Info | ||||
| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
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| Combination Type |
Vedotin
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