Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0DAATK
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| ADC Name |
HuMAB 5B1 targeted amanitin conjugate
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| Synonyms |
HuMab 5B1ADC; HuMab 5B1ATAC; HuMab 5B1 targeted amanitin conjugate (MabVax/Heidelberg Pharma AG); HuMAB 5B1-ATAC
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| Organization |
MabVax Therapeutics Holdings, Inc.; Heidelberg Pharma AG
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| Drug Status |
Investigative
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| Indication |
In total 1 Indication(s)
Pancreatic cancer [ICD11:2C10]
Investigative
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| Antibody Name |
5B1
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Antibody Info | ||||
| Antigen Name |
Sialyl Lewis A (sLeA)
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Antigen Info | ||||
| Payload Name |
Alpha-amanitin
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Payload Info | ||||
| Therapeutic Target |
DNA-directed RNA polymerase II subunit RPB2 (POLR2B); DNA-directed RNA polymerase III subunit RPC7 (POLR3G)
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Target Info | ||||
| Linker Name |
Undisclosed
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