Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0CGNUI
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| ADC Name |
Trastuzumab- (VC-PABC-MMAE)2
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| Synonyms |
Trastuzumab- (VC-PABC-MMAE)2
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| Organization |
Sogang University.; Osong Medical Innovation Foundation.; Sungkyunkwan University.; Yonsei University College of Medicine.
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| Drug Status |
Investigative
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| Drug-to-Antibody Ratio |
2
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| Structure |
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| Antibody Name |
Trastuzumab
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Antibody Info | ||||
| Antigen Name |
Receptor tyrosine-protein kinase erbB-2 (ERBB2)
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Antigen Info | ||||
| Payload Name |
Monomethyl auristatin E
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Undisclosed
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| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
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