Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0CBYIR
|
|||||
|---|---|---|---|---|---|---|
| ADC Name |
Maa-C6-Val-Cit-PAB-MMAE
|
|||||
| Synonyms |
Maa-C6-Val-Cit-PAB-MMAE
Click to Show/Hide
|
|||||
| Organization |
Academy of Military Medical Sciences
|
|||||
| Drug Status |
Investigative
|
|||||
| Drug-to-Antibody Ratio |
0.22
|
|||||
| Structure |
|
|||||
| Antibody Name |
undisclosed
|
|||||
| Antigen Name |
Receptor tyrosine-protein kinase erbB-2 (ERBB2)
|
Antigen Info | ||||
| Payload Name |
Monomethyl auristatin E
|
Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
|
Target Info | ||||
| Linker Name |
Maa-C6-Val-Cit-PAB
|
Linker Info | ||||
| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
|
|||||
| Combination Type |
Maa-C6-Val-Cit-PAB-MMAE
|
|||||