Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0CBHRO
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| ADC Name |
GPC-1 ADC 17
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| Synonyms |
GPC-1-ADC-17
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| Drug Status |
Investigative
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| Indication |
In total 3 Indication(s)
Adenocarcinoma [ICD11:2D40]
Investigative
Ovarian cancer [ICD11:2C73]
Investigative
Squamous cell cancer [ICD11:2D60-2D61]
Investigative
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| Drug-to-Antibody Ratio |
4.1
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| Antibody Name |
Anti-GPC1 mAb 01a026
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Antibody Info | ||||
| Antigen Name |
Glypican-1 (GPC1)
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Antigen Info | ||||
| Payload Name |
Monomethyl auristatin F
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Mc-Val-Cit-PABC
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Linker Info | ||||
| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
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| Combination Type |
VcMMAF
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