Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0BYNGR
|
|||||
|---|---|---|---|---|---|---|
| ADC Name |
TWI852077B-J1
|
|||||
| Synonyms |
J1
Click to Show/Hide
|
|||||
| Organization |
NOVARTIS AG
|
|||||
| Drug Status |
Investigative
|
|||||
| Drug-to-Antibody Ratio |
4
|
|||||
| Structure |
|
|||||
| Antibody Name |
Anti-cKIT Fab'1
|
Antibody Info | ||||
| Antigen Name |
Mast/stem cell growth factor receptor Kit (KIT)
|
Antigen Info | ||||
| Payload Name |
Monomethyl auristatin E
|
Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
|
Target Info | ||||
| Linker Name |
TWI852077B-C1-linker
|
Linker Info | ||||
| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
|
|||||
| Combination Type |
Compound (1)
|
|||||