Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0BWCTV
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| ADC Name |
ARX-305
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| Synonyms |
ARX 305; ARX-305; ARX305; NCB-002
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| Organization |
Ambrx, Inc.; Zhejiang Medicine Co., Ltd.; Novocodex Biopharmaceuticals Co., Ltd.
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| Drug Status |
Phase 1
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| Drug-to-Antibody Ratio |
2
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| Antibody Name |
Humanized anti-CD70 mAb
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Antibody Info | ||||
| Antigen Name |
CD70 antigen (CD70)
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Antigen Info | ||||
| Payload Name |
Monomethyl auristatin F
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Oxime-PEG3
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Linker Info | ||||
| Conjugate Type |
Site-specific conjugation through unnatural amino acid (pAF 121).
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