Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0BOJXK
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| ADC Name |
WO2017089890A1 ADC74
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| Synonyms |
Depatuxizumab_compound 25e (DAR 4)
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| Organization |
LegoChem Biosciences, Inc.
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| Drug Status |
Investigative
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| Indication |
In total 1 Indication(s)
Glioblastoma [ICD11:2A00]
Investigative
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| Drug-to-Antibody Ratio |
4
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| Antibody Name |
Depatuxizumab
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Antibody Info | ||||
| Antigen Name |
Epidermal growth factor receptor (EGFR)
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Antigen Info | ||||
| Payload Name |
Monomethyl auristatin E
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
WO2017089890A1_ADC74 linker
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| Conjugate Type |
Site-specific conjugation through nucleophilic lysines.
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