Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0BJXIT
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| ADC Name |
DL35D-DM1
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| Synonyms |
DL35D DM1
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| Drug Status |
Investigative
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| Indication |
In total 1 Indication(s)
HIV Infection [ICD11:1C60-1C62]
Investigative
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| Structure |
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| Antibody Name |
DL35D
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Antibody Info | ||||
| Antigen Name |
Envelope glycoprotein gp160 (env); Envelope glycoprotein gp41 (env)
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Antigen Info | ||||
| Payload Name |
Mertansine DM1
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Succinimidyl-4-(N-maleimidomethyl)cyclohexane-1-carboxylate (SMCC)
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Linker Info | ||||
| Conjugate Type |
Random conjugation through nucleophilic lysines.
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| Combination Type |
Emtansine
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