Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0AZSYY
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| ADC Name |
IC1-DM4
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| Synonyms |
IC1 DM4; IC1DM4
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| Drug Status |
Investigative
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| Indication |
In total 1 Indication(s)
Triple negative breast cancer [ICD11:2C60-2C65]
Investigative
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| Drug-to-Antibody Ratio |
3.83
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| Antibody Name |
Chimeric ICAM1 Anti-ody (clone #R6.5)
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Antibody Info | ||||
| Antigen Name |
Intercellular adhesion molecule 1 (ICAM1)
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Antigen Info | ||||
| Payload Name |
Mertansine DM4
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Mal-EBE-Mal
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Linker Info | ||||
| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
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