Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0ALXWV
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| ADC Name |
Anti-hEGFR (IgG4)-ABNO-DM-1: E4-AD
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| Synonyms |
Anti-hEGFR (IgG4)-ABNO-DM-1: E4-AD
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| Organization |
Department of Respiratory Medicine, Faculty of Medicine, Fukuoka University,.; Catalysis Chemistry Research Center, National Institute of Advanced Industrial Science and Technology (AIST).; Department of Applied Chemistry, Faculty of Engineering, Kyushu University.
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| Drug Status |
Investigative
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| Antibody Name |
anti-EGFR IgG4 antibody
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Antibody Info | ||||
| Antigen Name |
Epidermal growth factor receptor (EGFR)
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Antigen Info | ||||
| Payload Name |
Mertansine DM1
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
ABNO Linker
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Linker Info | ||||
| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
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