Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0AITIG
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| ADC Name |
ACD22-LC-K149C-10
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| Synonyms |
ACD22-LC K149C-10
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| Drug Status |
Investigative
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| Indication |
In total 1 Indication(s)
Diffuse large B-cell lymphoma [ICD11:2A81]
Investigative
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| Drug-to-Antibody Ratio |
2
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| Structure |
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| Antibody Name |
Anti-CD22-LC-K149C
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Antibody Info | ||||
| Antigen Name |
B-cell receptor CD22 (CD22)
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Antigen Info | ||||
| Payload Name |
PA-seco-CBI-dimer
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Payload Info | ||||
| Therapeutic Target |
Human Deoxyribonucleic acid (hDNA)
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Target Info | ||||
| Linker Name |
Mc-cBu-Cit
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Linker Info | ||||
| Conjugate Type |
Engineered cysteine residues at specific mAb sites to generate homogeneous conjugates.
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