Linker Information
General Information of This Linker
| Linker ID |
LIN0UTAIL
|
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|---|---|---|---|---|---|---|
| Linker Name |
Mc-cBu-Cit
|
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| Linker Type |
Cathepsin-cleavable linker
|
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| Antibody-Linker Relation |
Cleavable
|
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| Structure |
|
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| Formula |
C21H31N5O7
|
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| Isosmiles |
NC(=O)NCCCC(NC(=O)C1(C(=O)NCCCCCN2C(=O)C=CC2=O)CCC1)C(=O)O
|
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| InChI |
InChI=1S/C21H31N5O7/c22-20(33)24-12-4-6-14(17(29)30)25-19(32)21(9-5-10-21)18(31)23-11-2-1-3-13-26-15(27)7-8-16(26)28/h7-8,14H,1-6,9-13H2,(H,23,31)(H,25,32)(H,29,30)(H3,22,24,33)
|
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| InChIKey |
ZLYRGEVYMSYQJQ-UHFFFAOYSA-N
|
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| Pharmaceutical Properties |
Molecule Weight
|
465.507
|
Polar area
|
188
|
||
|
Complexity
|
33
|
xlogp Value
|
-0.6139
|
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|
Heavy Count
|
33
|
Rot Bonds
|
14
|
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|
Hbond acc
|
6
|
Hbond Donor
|
5
|
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Each Antibody-drug Conjugate Related to This Linker
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