General Information of This Antibody
Antibody ID
ANTI0QFHEP
Antibody Name
Anti-TPP-7511
Organization
REGENERON PHARMACEUTICALS, INC.
Synonyms
Anti-TPP-7511
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Antibody Type
Monoclonal antibody (mAb)
Antibody Subtype
Humanized lgG
Antigen Name
Undisclosed
 Antigen Info 
Click to Show/Hide the Sequence Information of This Antibody
Each Antibody-drug Conjugate Related to This Antibody
Full Information of The Activity Data of The ADC(s) Related to This Antibody
US12144865B2 34te-4 [Investigative]
Revealed Based on the Cell Line Data
Click To Hide/Show 1 Activity Data Related to This Level
Experiment 1 Reporting the Activity Date of This ADC [1]
Efficacy Data Half Maximal inhibitory Concentration (IC50)Human PBMC
0.329 nM
Positive HER2 expression (HER2+++/++)
Method Description
Tables 1b and 1c below set out the IC50 values for representative working examples from this assay
In Vitro Model Breast inflammatory carcinoma KPL4 cells CVCL_5310
References
Ref 1 Antibody drug conjugates with enzymatically cleavable groups