Antibody Information

General Information of This Antibody
Antibody ID
ANI0MYANI
Antibody Name
Anti-integrin alpha10 mAb
Antibody Type
Monoclonal antibody (mAb)
Antibody Subtype
Humanized IgG2
Antigen Name
Integrin alpha-10 (ITGA10)
  Antigen Info 
Each Antibody-drug Conjugate Related to This Antibody
Full Information of The Activity Data of The ADC(s) Related to This Antibody
Anti-alpha10-SAP [Investigative]
 ADC Info 
Revealed Based on the Cell Line Data
Click To Hide/Show 1 Activity Data Related to This Level
Experiment 1 Reporting the Activity Date of This ADC [1]
Efficacy Data Half Maximal Inhibitory Concentration (IC50)
69.00 nM
Positive ITGA10 expression (ITGA10+++/++)
Method Description
Viability analysis of U3046 mg GBM cells after treatment with increasing concentration of anti-alpha10-SAP or anti-ctrl-SAP for 96 h.
In Vitro Model Glioblastoma U3046MG cells CVCL_IR78
References
Ref 1 Integrin 10, a Novel Therapeutic Target in Glioblastoma, Regulates Cell Migration, Proliferation, and Survival. Cancers (Basel). 2019 Apr 25;11(4):587. doi: 10.3390/cancers11040587.

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